Spermidine extends lifespan in every organism tested — from yeast to mice. A 2024 study shows it’s essential for fasting-induced autophagy. But can supplements replicate the effect?
Yale researchers found that depleting one amino acid converted white fat to calorie-burning brown fat in mice — without cutting calories or losing muscle.
A 2025 study tracked the same rowers across high and low training loads. Higher intensity boosted beneficial SCFAs but lowered bacterial diversity.